产品货号:
Z23171
中文名称:
PINX1抗体
英文名称:
Anti-PINX1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PINX1 Antibody |
指标别名 | LPTL;LPTS;PIN2 interacting protein 1;Pin2 interacting protein X1;PINX1;Protein 67 11 3;TRF1 interacting protein 1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | IHC,ELISA |
基因名称 | PINX1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human PinX1 |
计算分子量 | 37KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | PINX1,also known as PIN2 interacting protein 1,is a telomerase inhibitor and a possible tumor suppressor.It is mapped to 8p23.Over-expression of PINX1 results in decreased telomerase activity,telomere shortening,and induction of crisis.Reduction of PINX1 leads to an increase in telomerase activity and elongation of telomeres.PINX1 differs from other proteins that regulate telomere length in that it acts on telomerase while other proteins adjust telomere length without affecting telomerase activity.The PINX1 budding yeast orthologue Gnop1 inhibits telomerase by isolating the uncomplexed TERT protein so that it cannot associate with the telomerase template RNA,which prevents telomerase from being assembled.However,in humans,PINX1 impedes already assembled telomerase. |
Uniprot ID | Q96BK5 |
基因名全称 | PIN2/TERF1-interacting telomerase inhibitor 1 |
蛋白名全称 | PIN2/TERF1-interacting telomerase inhibitor 1 |
推荐稀释比 | IHC 1:100~1:300 ELISA 1:20000 |
相关搜索:PINX1抗体,PINX1多抗,Anti-PINX1 Antibody